Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...

In the new study, the team used the model to demonstrate that as Alzheimer's pathology accumulates in the brain, specific types of immune cells called CT8+ T Cells surge into the brain and amplify the ...

MIT scientists have developed a new 3D human brain tissue model that could change how researchers study neurological diseases. The platform, called Multicellular Integrated Brains or miBrains, ...

Neuronal death is the indisputable endgame of Alzheimer’s disease, but what does the killing, and how? To try to solve the mystery, researchers have staged increasingly complex crime scenes in ...

A research team in South Korea has successfully developed a novel technology that combines nanoparticles with stem cells to ...

3D microtissues, resembling human tissue in both form and function, have been shown to be amenable to parallelized screening approaches. However, most 3D screens rely on global endpoints such as ...

Organoids—self-organizing, self-reproducing structures that serve as 3D in vitro models—date back to 2009. Back then, researchers at the Hubrecht Institute led by Hans Clevers, PhD, introduced a ...

Explore Clecell and CLE-iFTs, innovations in bioprinted skin technology using human induced pluripotent stem cells for better ...

The lab-made 3D liver model serves as a human relevant platform for analyzing the progressive stages of the liver disease, ...

A biomedical researcher combining advanced mouse models with human-based and computational approaches explains why we can’t ...