Our discovery set comprised 31 pRCCs and paired normal tissue or peripheral blood (Table 1). Three tumours were separate foci from case GK116; these appeared to be grossly distinct lesions and were ...

In this study, we further demonstrate that the contiguous genomic representation of only one of the partner genes of a chimeric fusion on the capture microarray assay was sufficient to identify also ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, No. 14 (Jul. 15, 1992), pp. 6535-6539 (5 pages) A vector-transformation system is described that permits ...

DLGAP5 is proposed as a causal gene related to oocyte meiosis disorder for the first time. It expanded the current spectrum of pathogenic genes responsible for the phenotype of oocyte maturation and ...

Healthy cells work hard to maintain the integrity of our DNA, but occasionally, a chromosome can get separated from the others and break apart during cell division. The tiny fragments of DNA then get ...

A new layer in the complex organization of chromosomes has been discovered. Scientists have now shown that chromosomes fold in a series of contiguous "yarns" that harbor groups of genes and regulatory ...

Healthy cells work hard to maintain the integrity of our DNA, but occasionally, a chromosome can get separated from the others and break apart during cell division. The tiny fragments of DNA then get ...

This is a preview. Log in through your library . Abstract Loss of chromosome 18q21 is well documented in colorectal cancer, and it has been suggested that this loss targets the DCC, DPC4/SMAD4, and ...

Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking in ...

Seattle biotech company Phase Genomics announced Wednesday that it received two National Institutes of Health (NIH) grants totaling $3.9 million. The funding, which runs for three years, will help pay ...