Impact of BRCA1 gene alterations on tumor characteristics and clinical outcome in ovarian cancer (OC) patients. Background: Advanced ovarian clear cell carcinomas (OCCCs) are notoriously drug ...

Oligonucleotide array comparative genomic hybridization (aCGH) was performed on 42 microdissected high-grade serous ovarian tumor samples. aCGH segments were obtained and a prediction Cox model was ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

The sample-to-result times were compared with state-of-the-art array-based comparative genomic hybridization (aCGH). Researchers also evaluated sensitivity and specificity of nanopore sequencing for ...

While gene flow can reduce the potential for local adaptation, hybridization may conversely provide genetic variation that increases the potential for local adaptation. Hybridization may also affect ...

Between missing chunks of chromosomes and single nucleotide polymorphisms (SNPs) lies a vast middle ground of genomic alterations. Among these are copynumber variations (CNVs) - the differences ...

In a recent study posted to the bioRxiv* preprint server, researchers surveilled coronaviruses (CoV) found in bats via targeted genomic sequencing. Study: Targeted genomic sequencing with probe ...

Using SNP-CGH to Profile for Amplifications, Duplications, and Deletions The beginnings of personalized medicine have been forged by recent advances in SNP genotyping technologies. It is now possible ...

In a recent study, scientists from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) have utilized ...