Dynamic programming algorithms are a good place to start understanding what's really going on inside computational biology software. The heart of many well-known programs is a dynamic programming ...

We develop a novel framework, the implicit hitting set approach, for solving a class of combinatorial optimization problems. The explicit hitting set problem is as follows: given a set U and a family ...

Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.