RNAi (RNA interference) and CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) screening are two powerful techniques at the forefront of functional genomics research. Both techniques ...

Over the past few decades, biomedical researchers and neuroscientists have devised increasingly advanced techniques to study and alter neurophysiological processes. These include CRISPR (Clustered ...

Phenotypic CRISPR Screening: Looking Beyond Cell Viability To Study Complex Genetic Interactions from thescientistllc on Vimeo. CRISPR screening, whether using knockout, activation, or inhibition ...

Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).

CRISPR-based screening identifies H2AZ1 as a driver of cellular senescence. (A) Schematic of CRISPR-based loss-of-function (LOF) screening for histone variant-associated genes (HVRGs) to identify ...

DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...

The tomato plant genome is divided into gene families. For each group of similar genes, a unique CRISPR unit is designed to alter their function (in total, over 15,000 CRISPR units were designed).