The transcription process sits at the heart of the gene expression pathway. The thousands of genes found in the mammalian genome can fluctuate between 'on' and 'off' states and produce the required ...

A direct gene transfer into defined sites on chromosomes has the potential for both elucidating the molecular mechanisms underlying genome function and for developing clinical applications such as ...

Recombinant protein expression is an essential pillar of biomedical research. Efforts from enzyme discovery to protein structure-function study to development of drugs and biological therapeutics all ...