A technique can determine for the first time how frequently, and exactly where, a molecular event called 'backtracking' occurs throughout the genetic material (genome) of any species. A technique can ...

It must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues.

This study presents a comprehensive benchmarking of human-derived transcription activation domains (hTADs) for use in CRISPR-based artificial ...

A major medical milestone took place in May 2025, when doctors at the Children’s Hospital of Philadelphia used CRISPR-based ...

Please provide your email address to receive an email when new articles are posted on . The Nobel Assembly at Karolinska Institutet in Sweden announced the honor today. Victor R. Ambros, PhD, and Gary ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

Highly repetitive regions of junk DNA may be the key to a newly discovered mechanism for gene regulation. The discovery during the Human Genome Project in the early 2000s that we humans have only ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

Every cell in our body starts out with the same set of genetic instructions, or DNA. Yet only some of these genes are expressed in each cell, leading to the production of proteins that perform the ...

Although HPVs do express some unspliced mRNAs (Figure 2), most HPV mRNAs are the products of constitutive and alternative splicing. Constitutive splicing is where every intron in the primary RNA ...