Physician referral patterns and use of adjuvant therapy among stage IB-IIIA non-small cell lung cancer (NSCLC) patients (2010-2017). This is an ASCO Meeting Abstract from the 2022 ASCO Annual Meeting ...

A recent study unveils new insights into the complex regulatory mechanisms behind strawberry fruit ripening. By analyzing histone modifications, researchers have mapped a detailed chromatin structure ...

Strands of DNA wrapped around a histone. Credit: Molekuul/Science Source Histones are among the most abundant proteins in the body. They act as spools that help compact DNA so our enormous genomes ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

BUFFALO, NY- June 30, 2022 – A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 12, entitled, “Time makes histone H3 modifications drift in mouse liver.” Aging is ...

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells. By ...

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

Chemical changes to histones, the proteins that help to pack and organize DNA inside cells, play a key role in determining what genes will be consistently activated over the course of an animal or ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...