Business Wire

Drug Development: PhinC Makes Available to Biotech the Best Modeling Tools Used by Big Pharma

EVRY, France--(BUSINESS WIRE)--PhinC Development, a company specialized in early drug development strengthens its offer in pharmacometrics. This new PBPK service (Physiologically Based Pharmacokinetic ...
JSTOR Daily

The Implications of Using a Physiologically Based Pharmacokinetic (PBPK) Model for Pesticide Risk Assessment

Background: A physiologically based pharmacokinetic (PBPK) model would make it possible to simulate the dynamics of chemical absorption, distribution, metabolism, and elimination (ADME) from different ...
JSTOR Daily

Pharmacokinetics of Toxic Chemicals in Breast Milk: Use of PBPK Models to Predict Infant Exposure

This is a preview. Log in through your library . Abstract Factors controlling the transfer of potentially toxic chemicals in the breast milk of nursing mothers include both chemical characteristics, ...
technologynetworks

Physiologically-based pharmacokinetic (PBPK) model for prediction of midazolam pharmacokinetics after intranasal administration in children

Purpose: To predict midazolam absorption and pharmacokinetics (PK) after intranasal (i.n.) administration in young children. Methods: The absorption and PK of midazolam were simulated using ...
News Medical

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China, in December 2019. Studies have shown that between 3% to 8% of coronavirus disease 2019 (COVID-19) ...