We transformed care for advanced prostate cancer, by validating inhibitors of androgen production as an effective cancer ...

Through studies that were amongst the largest of their kind, we identified several genes involved in breast and/or ovarian cancer predisposition such as CHEK2, BRIP1, ATM, PALB2, RAD51C and RAD51D.

In a major step forward for cancer drug discovery, researchers have demonstrated how computational simulations can unravel the complex role of water molecules in drug ...

We identified many of the cancer-causing chemicals in cigarette smoke and coal tar – including the first pure carcinogen ever to be isolated.

DJ and music promoter, Godfrey Fletcher, was diagnosed with prostate cancer in 2015 at the age of 47, shortly after his father was also diagnosed with the same disease. Since then, Godfrey has made it ...

We applied the principle of synthetic lethality to discover a novel strategy for cancer treatment for patients with BRCA1 or ...

We played a major role in revealing the biochemical steps of the RAS-RAF-MAP kinase pathway. We identified one of the major ...

PI3 kinase is a lipid signalling enzyme which plays a key role in the development and progression of many cancers as a result ...

Tony McHale (pictured above) discovered he had an alteration in the BRCA2 gene at the age of 61, putting him at a much higher risk of developing prostate cancer. Shortly after, Tony joined the IMPACT ...

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We were the first in Europe to develop chemotherapeutic agents. We discovered, and with The Royal Marsden developed, the chemotherapy drugs busulfan, chlorambucil, melphalan and carboplatin, which are ...

We provided the first conclusive evidence that the basic cause of cancer is damage to DNA. The discovery changed scientific opinion dramatically and marked a turning point for cancer research.