Acetylation of lysine residues in the tail domain of histone H3 is well characterized, but lysine residues in the histone globular domain are also acetylated. Histone modifications in globular domain ...

Cancer is increasingly recognized as a systemic disease influenced by complex interactions between genetic, metabolic, immunologic, and environmental ...

Priority Research Communication by Professor Yogesh Dwivedi and colleagues at the University of Alabama at Birmingham reports original, peer-reviewed findings demonstrating that long noncoding RNAs ...

An epigenetic factor that is essential for producing mature egg cells in mice has been identified by RIKEN researchers for ...

NANOG has multifaceted roles in naïve hESCs, orchestrating transcriptional, metabolic, and epigenetic signatures in naïve hESCs, and governing acetyl-CoA synthesis, bivalent metabolism, and redox ...

An epigenetic sensor uses a 21st amino acid to illuminate protein dynamics in real time to observe changes within cells.

This valuable work provides new insights into the role of lysine acetylation of alpha-synuclein, the protein involved in Parkinson's Disease. The evidence is mostly solid, but the claims around the ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how ...