Research led by Washington State University scientists supports a novel theory that the innate immune system people are born with, can respond differently to specific pathogens. This quality, known as ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways—ways that have important implications for the development of ...

Innate immunity constitutes the body’s first line of defence against invading pathogens. This ancient, evolutionarily conserved system is activated within minutes of encountering foreign agents, ...

Researchers from Penn’s School of Dental Medicine discovered that training the innate immune system may lead to increased bone loss in inflammatory conditions such as periodontitis and arthritis.

Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. Surprisingly, at the same time a cell ...

An investigational Toll-like receptor (TLR) antagonist was effective in reducing biomarkers and clinical symptoms of systemic lupus erythematosus (SLE) in a pilot trial, evidence that the innate ...

Monash University researchers have discovered a key mechanism in the body's immune system that helps control the inflammatory response to infection. The discovery could help pave the way for more ...

Having a robust enough immune system to live a longer life may come at the cost of chronic inflammation. Some immune cells undergo an inflammatory form of death that evolved to protect us from ...