Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...
Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...
Gene expression and features of the DNA–protein complex chromatin were mapped together at high spatial resolution in tissue sections of the mouse or human brain. This spatially resolved technology ...
Controlling gene expression is essential to growth, development, and sustained life. This requires regulating the spacial, temporal, and developmental expression of genes in a wide diversity of cell ...
Your skin cells are clearly different from your brain cells even though they both develop in the same person and carry the same genes. They are different because each cell type expresses a particular ...
Although HPVs do express some unspliced mRNAs (Figure 2), most HPV mRNAs are the products of constitutive and alternative splicing. Constitutive splicing is where every intron in the primary RNA ...
A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive ...
In a comprehensive preclinical program, NGN-401 demonstrated robust therapeutic and safety benefits, delivering MECP2 to key brain regions affected by Rett syndrome NGN-401 utilizes Neurogene’s ...