The Institute of Cancer Research, London

How cells become cancerous

We played a major role in revealing the biochemical steps of the RAS-RAF-MAP kinase pathway. We identified one of the major ...
ascopubs.org

Clinical Activity of Mitogen-Activated Protein Kinase Inhibitors in Patients With MAP2K1 (MEK1)-Mutated Metastatic Cancers

NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...
Labmate Online

Experimental ERK inhibitor shows promise in rare histiocytic cancers

Memorial Sloan Kettering Cancer Center has reported promising early clinical results for ulixertinib, a novel extracellular ...
WFLA News Channel 8

‘Game-changer for West Tampa:’ Riverwalk expansion adds miles of pathways

TAMPA, Fla. (WFLA)—The City of Tampa announced the groundbreaking of the new west Riverwalk project. The West River BUILD project will have more than five miles of roadway safety improvements and new ...
C&EN

RSK Inhibition Rewires Kinase Networks and Triggers Cascading Pathway Disruption in Esophageal Cancer

Institute of Neurology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu 610072, China Chinese Academy of Sciences Sichuan Translational Medicine ...
Frontiers

Potential signaling pathways, biomarkers, natural drugs, and chronic myeloid leukemia therapeutics

1 Department of Basic Medical Sciences, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia 2 King Abdullah International Medical Research Center (KAIMRC) ...