Researchers at Kanazawa University have used nanoendoscopy atomic force microscopy to create nanoscale maps of nuclear ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

Pharmacogenomic Strategies Provide a Rational Approach to the Treatment of Cisplatin-Resistant Patients With Advanced Cancer We used immunohistochemistry to assess histone 3 lysine 4 dimethylation ...

Scientists have observed changes to the gene-regulating factors during zebrafish development and discovered that modifications to 'histone H3', one of the proteins around which DNA is bound, play an ...

A recent study unveils new insights into the complex regulatory mechanisms behind strawberry fruit ripening. By analyzing histone modifications, researchers have mapped a detailed chromatin structure ...

Scientists at Tokyo Institute of Technology (Tokyo Tech) observed changes to the gene-regulating factors during zebrafish development and discovered that modifications to "histone H3", one of the ...

Molecular biologists decode the epigenetic silencing of problematic retroviral gene sequences. LMU molecular biologist Gunnar Schotta decodes the epigenetic silencing of problematic retroviral gene ...

Salt stress remains a critical challenge for plant growth, especially in crops like pea (Pisum sativum L.). This study explores the role of histone modifications in regulating pea's response to salt ...