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Prognostic, predictive, and surrogate biomarkers in men with castration resistant metastatic prostate cancer
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🧬 Can prostate cancer be switched off? Here’s what researchers have just discovered about castration-resistant prostate cancer (CRPC) the advanced form that keeps growing even when testosterone is eliminated. It turns out one crucial tumor suppressor gene PTEN is often shut down in these aggressive cases. And the “switch”? A lesser-known molecule called KDM3B. ✅ When KDM3B is high → PTEN stays ON → Cancer slows down. ❌ When KDM3B is low → PTEN turns OFF → Cancer accelerates. Most CRPC patients
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🧬 Can prostate cancer be switched off? Here’s what researchers have just discovered about castration-resistant prostate cancer (CRPC) the advanced form that keeps growing even when testosterone is eliminated. It turns out one crucial tumor suppressor gene PTEN is often shut down in these aggressive cases. And the “switch”? A lesser-known molecule called KDM3B. ✅ When KDM3B is high → PTEN stays ON → Cancer slows down. ❌ When KDM3B is low → PTEN turns OFF → Cancer accelerates. Most CRPC patients
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